#KGL SKIN STUDY CENTER SKIN#

#KGL SKIN STUDY CENTER SKIN#

In the health care personnel handwash study, transepidermal water loss was less than that for skin treated with the conventional CHG product ( P <. 004) better on evaluations of visual dryness and erythema and showed greater improvement in the level of hydration ( P <. In general, skin treated with the waterless CHG/ethanol product scored significantly ( P <. Results: Fifty-eight subjects were enrolled in the 2 studies and received both treatments. Transepidermal water loss was measured by an evaporimeter, and the skin surface hydration level was measured by an electrical conductance meter.

Subjects completed a self-assessment questionnaire on skin condition. An expert grader evaluated skin for dryness, erythema, and roughness. Trained technicians applied treatments 6 times (for a surgical scrub study) or 24 times (for a personnel handwash study) daily to the hands of healthy volunteers during 5 days of controlled washing. Methods: Two randomized, blinded, bilateral comparison studies evaluated skin condition during use of 2 antiseptic hand preparation products: a new 1% chlorhexidine gluconate (CHG)/61% wt/wt ethanol antiseptic hand preparation in a unique emollient system for waterless/brushless application and a conventional 4% CHG antimicrobial product that is applied with water and a scrub brush. Background: Hand-cleansing products that are milder to the skin of health care personnel are being developed, but the available methodologies to appropriately evaluate these products and quantify differences are not generally being applied in well-controlled studies.

Kgl skin study center